Corentine GUILLOTON

It has long been recognized that invertebrate immunity relies exclusively on an innate immune system, lacking memory and non-specific. However, this view has been challenged by several studies demonstrating the ability of many invertebrates to modulate their immune response based on their immunological experience. This phenomenon, known as priming or immune memory, allows individuals to specifically recognize a pathogen they encountered once earlier in life and to combat it more effectively through increased immunocompetence.
While this phenomenon is well described in insects and snails, little data is available regarding mussels. The MEMORY project aims to explore immune memory in marine mussels of the Mytilus genus. Its main objective is to characterize the immune memory response in terms of duration and specificity, and to identify the effectors that govern it